ZFIN ID: ZDB-GENE-060519-5
Gene Name: abl-interactor 2b
Gene Symbol: abi2b    Nomenclature History

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Previous Name: zgc:136560

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have SH3 domain binding activity. Predicted to be involved in actin polymerization or depolymerization. Predicted to localize to lamellipodium. Orthologous to human ABI2 (abl interactor 2).
Genome Resources: Alliance (1),  Gene:692331 (1),  Ensembl(GRCz11):ENSDARG00000014875 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16444 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18833 Point Mutation Unknown Splice Site ENU
    sa20645 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abi2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abi2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin polymerization or depolymerization (more)
    Cellular Component lamellipodium (more)
    Molecular Function SH3 domain binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abi2b-201 (1)    Ensembl 1961
    abi2b-202 (1)    Ensembl 1725
    abi2b-203 (1)    Ensembl 1352
    abi2b-204 (1)    Ensembl 835
    abi2b-205 (1)    Ensembl 596
    abi2b-206 (1)    Ensembl 1473
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abi2b No data available
    MARKER RELATIONSHIPS
    abi2b Contained in: [BAC] CH73-374O20 (1)
    abi2b Encodes: [cDNA] MGC:136560 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045297 (1) 1906 nt
    Genomic GenBank:CU929158 (1) 89705 nt
    Select Tool
    Polypeptide UniProtKB:I3ITI8 (1) 574 aa
    Sequence Information (all 41)
    ORTHOLOGY for abi2b ( Chr: 6 )
    CITATIONS (17)