ZFIN ID: ZDB-GENE-060519-23
Gene Name: solute carrier family 6 member 1a
Gene Symbol: slc6a1a    Nomenclature History

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Previous Names: fj43h03, wu:fj43h03, zgc:136569

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have gamma-aminobutyric acid:sodium symporter activity and neurotransmitter binding activity. Predicted to be involved in neurotransmitter transport. Predicted to localize to the axon; cell surface; and plasma membrane. Is expressed in nervous system. Orthologous to human SLC6A1 (solute carrier family 6 member 1).
Genome Resources: Alliance (1),  Gene:692318 (1),  Ensembl(GRCz11):ENSDARG00000045944 (2)
GENE EXPRESSION
All Expression Data: text only from Cocco et al., 2017
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc6a1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myoclonic-atonic epilepsy 616421
DISEASE ASSOCIATED WITH slc6a1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neurotransmitter transport (more)
Cellular Component integral component of membrane (more)
Molecular Function gamma-aminobutyric acid:sodium symporter activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Family IPR002980 Sodium:neurotransmitter symporter, GABA, GAT-1
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA slc6a1a-201 (1)    Ensembl 2429
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM slc6a1a No data available
MARKER RELATIONSHIPS
slc6a1a Contained in: [BAC] CH211-117K14 (1)
slc6a1a Encodes: [EST] fj43h03
[cDNA] MGC:136569 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001045287 (1) 2430 bp
Genomic GenBank:CR354596 (1) 172749 bp
Select Tool
Polypeptide UniProtKB:F1QUY7 (1) 679 aa
Sequence Information (all 14)
ORTHOLOGY for slc6a1a ( Chr: 23 )
CITATIONS (21)