ZFIN ID: ZDB-GENE-060512-226
Gene Name: NDRG family member 4
Gene Symbol: ndrg4    Nomenclature History

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Previous Names: si:ch211-194m7.2 (1), zgc:136766 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Involved in cardiac muscle cell proliferation; clustering of voltage-gated sodium channels; and heart looping. Predicted to localize to cytoplasm. Is expressed in basal plate midbrain region; cardiovascular system; nervous system; and spinal cord neural tube. Orthologous to human NDRG4 (NDRG family member 4).
Genome Resources: Alliance (1),  Gene:692305 (1),  Ensembl(GRCz11):ENSDARG00000103937 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44247 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ndrg4
    1
    MO1-ndrg4 N/A 1
    MO2-ndrg4 N/A 2
    DISEASE ASSOCIATED WITH ndrg4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ndrg4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle cell proliferation (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript ndrg4-202 (1)    Ensembl 712
    mRNA ndrg4-201 (1)    Ensembl 6116
    ndrg4-203 (1)    Ensembl 628
    ndrg4-204 (1)    Ensembl 1800
    ndrg4-205 (1)    Ensembl 763
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ndrg4 No data available
    MARKER RELATIONSHIPS
    ndrg4 Contained in: [BAC] CH211-194M7 (1)
    ndrg4 Encodes: [EST] eu2445 (1)
    [cDNA] MGC:136766 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045173 (1) 6116 nt
    Genomic GenBank:AL772241 (1) 154972 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICQ1 (1) 352 aa
    Sequence Information (all 36)
    ORTHOLOGY for ndrg4 ( Chr: 25 )
    CITATIONS (28)