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ZIRC
ZFIN ID: ZDB-GENE-060503-925
Gene Name: carnitine palmitoyltransferase 1Aa (liver)
Gene Symbol: cpt1aa    Nomenclature History

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Previous Names: cpt1a, si:dkey-56p7.8

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have carnitine O-palmitoyltransferase activity. Involved in lymphangiogenesis and regulation of fatty acid beta-oxidation. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Is expressed in liver and male organism. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A).
Genome Resources: Alliance (1),  Gene:558088 (1),  Ensembl(GRCz11):ENSDARG00000059770 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Wild-type Stages, Structures: Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16862 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34169 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cpt1aa N/A 1
    MO2-cpt1aa N/A 1
    DISEASE ASSOCIATED WITH cpt1aa HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    carnitine palmitoyltransferase I deficiency Alliance CPT deficiency, hepatic, type IA 255120
    DISEASE ASSOCIATED WITH cpt1aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lymphangiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transferase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cpt1aa-201 (1)    Ensembl 2325
    cpt1aa-202 (1)    Ensembl 3354
    cpt1aa-203 (1)    Ensembl 440
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cpt1aa No data available
    MARKER RELATIONSHIPS
    cpt1aa Contained in: [BAC] DKEY-56P7 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044854 (1) 2476 bp
    Genomic GenBank:AL929208 (1) 189608 bp
    Select Tool
    Polypeptide UniProtKB:A0A1L1U0X8 (1) 774 aa
    Sequence Clusters UniGene:134089 (1)
    Sequence Information (all 15)
    ORTHOLOGY for cpt1aa ( Chr: 7 )
    CITATIONS (46)