ZFIN ID: ZDB-GENE-060503-889
Gene Name: dystrobrevin binding protein 1b
Gene Symbol: dtnbp1b    Nomenclature History

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Previous Name: si:ch211-285p6.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to be involved in several processes, including anterograde synaptic vesicle transport; platelet dense granule organization; and regulation of synaptic vesicle exocytosis. Predicted to localize to several cellular components, including BLOC-1 complex; neuron projection; and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 7 and schizophrenia. Orthologous to human DTNBP1 (dystrobrevin binding protein 1).
Genome Resources: Alliance (1),  Gene:556784 (1),  Ensembl(GRCz11):ENSDARG00000055206 (1)
GENE EXPRESSION
All Expression Data: Fig. 4 from Hsu et al., 2013
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013432Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013433Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013434Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11373 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17933 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dtnbp1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Hermansky-Pudlak syndrome 7 Alliance Hermansky-Pudlak syndrome 7 614076
    DISEASE ASSOCIATED WITH dtnbp1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterograde synaptic vesicle transport (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dtnbp1b-201 (1)    Ensembl 843
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dtnbp1b No data available
    MARKER RELATIONSHIPS
    dtnbp1b Contained in: [BAC] CH211-285P6 (1)
    dtnbp1b Encodes: [cDNA] MGC:162778 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044814 (1) 1069 nt
    Genomic GenBank:BX842609 (1) 177481 nt
    Select Tool
    Polypeptide UniProtKB:A3KNZ4 (1) 220 aa
    Sequence Information (all 18)
    ORTHOLOGY for dtnbp1b ( Chr: 19 )
    CITATIONS (23)