ZFIN ID: ZDB-GENE-060503-803
Gene Name: coenzyme Q8B
Gene Symbol: coq8b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: adck4 (1), si:dkey-114g7.2

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have kinase activity. Involved in glomerular basement membrane development and glomerular visceral epithelial cell development. Predicted to localize to extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 9. Orthologous to human COQ8B (coenzyme Q8B).
Genome Resources: Alliance (1),  Gene:799071 (1),  Ensembl(GRCz11):ENSDARG00000101130 (1)
GENE EXPRESSION
All Expression Data: Fig. S7 from Burkhalter et al., 2019
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Segmentation:5-9 somites (11.66h-14.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6367 Point Mutation Unknown Premature Stop ENU
sa24977 Point Mutation Unknown Splice Site ENU
sa32019 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35821 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-coq8b N/A 1
    MO2-coq8b N/A 1
    MO3-coq8b N/A 1
    DISEASE ASSOCIATED WITH coq8b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    nephrotic syndrome type 9 Alliance Nephrotic syndrome, type 9 615573
    DISEASE ASSOCIATED WITH coq8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glomerular basement membrane development (more)
    Cellular Component cytoplasm (more)
    Molecular Function NOT   protein kinase activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA coq8b-201 (1)    Ensembl 2161
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM coq8b No data available
    MARKER RELATIONSHIPS
    coq8b Contained in: [BAC] DKEY-114G7 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001336274 (1)
    Genomic GenBank:CR318657 (1) 151250 nt
    Select Tool
    Polypeptide UniProtKB:A3QJU3 (1) 624 aa
    Sequence Information (all 11)
    ORTHOLOGY for coq8b ( Chr: 15 )
    CITATIONS (22)