Gene

gsk3aa

ID

ZDB-GENE-060503-796

Name

glycogen synthase kinase 3 alpha a

Symbol

gsk3aa Nomenclature History

Previous Names

sb:eu851
si:ch211-39e15.2
zgc:158379

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cell surface receptor signaling pathway; negative regulation of signal transduction; and regulation of neuron projection development. Predicted to localize to axon; cytosol; and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is expressed in testis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu851 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gsk3aa Human Ortholog

No data available

Associated With gsk3aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR039192	Glycogen synthase kinase 3, catalytic domain
Family	IPR050591	Glycogen Synthase Kinase-3
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily