ZFIN ID: ZDB-GENE-060503-796
Gene Name: glycogen synthase kinase 3 alpha a
Gene Symbol: gsk3aa    Nomenclature History

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Previous Names: sb:eu851, si:ch211-39e15.2, zgc:158379

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cell surface receptor signaling pathway; negative regulation of signal transduction; and regulation of neuron projection development. Predicted to localize to axon; cytosol; and nucleus. Is expressed in testis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).
Genome Resources: Alliance (1),  Gene:560194 (1),  Ensembl(GRCz11):ENSDARG00000029501 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu851]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29147 Point Mutation Unknown Premature Stop ENU
sa36771 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gsk3aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gsk3aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component axon (more)
    Molecular Function ATP binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gsk3aa-201 (1)    Ensembl 2634
    gsk3aa-202 (1)    Ensembl 805
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gsk3aa No data available
    MARKER RELATIONSHIPS
    gsk3aa Contained in: [BAC] CH211-39E15 (1)
    gsk3aa Encodes: [EST] eu851 (1)
    [cDNA] MGC:158379 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044921 (1) 2634 nt
    Genomic GenBank:BX004874 (1) 165154 nt
    Select Tool
    Polypeptide UniProtKB:Q1LYN4 (1) 462 aa
    Sequence Information (all 21)
    ORTHOLOGY for gsk3aa ( Chr: 19 )
    CITATIONS (22)