Gene

foxo6b

ID

ZDB-GENE-060503-776

Name

forkhead box O6 b

Symbol

foxo6b Nomenclature History

Previous Names

foxo6
foxo6a
si:ch211-206a7.2 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in glucose homeostasis; insulin receptor signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nucleus. Is expressed in central nervous system; eye; and pericardial region. Orthologous to human FOXO6 (forkhead box O6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxo6b Human Ortholog

No data available

Associated With foxo6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Domain	IPR032067	FOXO protein, transactivation domain
Domain	IPR032068	FOXO protein, KIX-binding domain
Domain	IPR047410	Forkhead box protein O6, forkhead domain
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily