Gene

edn2

ID
ZDB-GENE-060503-774
Name
endothelin 2
Symbol
edn2 Nomenclature History
Previous Names
  • si:ch211-202b2.2
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have endothelin B receptor binding activity and hormone activity. Predicted to be involved in several processes, including positive regulation of prostaglandin-endoperoxide synthase activity; regulation of systemic arterial blood pressure by endothelin; and vein smooth muscle contraction. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Goldman et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With edn2 Human Ortholog
No data available
Associated With edn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019764 Endothelin-like toxin, conserved site
Domain IPR001928 Endothelin-like toxin
Family IPR015658 Endothelin-2
Family IPR020475 Endothelin
Domain Details Per Protein
Protein Length Endothelin Endothelin-2 Endothelin-like toxin Endothelin-like toxin, conserved site
UniProtKB:Q1MT02 164
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations