ZFIN ID: ZDB-GENE-060503-766
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Gene Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
Gene Symbol: plekhg5a
Sequence Ontology ID : SO:0000704

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Previous Names: plekhg5 (1), si:ch211-15p9.7, syx-a (1), syx (1)

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017777Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa31827 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa35079 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa41834 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa41835 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 8 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH plekhg5a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease recessive intermediate C Charcot-Marie-Tooth disease, recessive intermediate C 615376
    Spinal muscular atrophy, distal, autosomal recessive, 4 611067
    DISEASE ASSOCIATED WITH plekhg5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR029071 (1)
  • InterPro:IPR035899 (1)
  • InterPro:IPR040181 (1)
    		•
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
    		•
  • Pfam:PF00621 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA plekhg5a-001 (1) 4936
    Select Tool
    plekhg5a-002 (1) 434
    Select Tool
    ncRNA plekhg5a-003 (1) 407
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM plekhg5a No data available
    MARKER RELATIONSHIPS
    plekhg5aContained in: [BAC] CH211-15P9 (1) (order this), DKEY-27B23 (1) (order this)
    plekhg5aEncodes: [EST] wz11960 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA WashUZ:wz11960 775bp
    Genomic GenBank:BX072564 (1) 205057bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R1Q2 (1) 1157aa
    Select Tool
    Sequence Information (all 8)
    OTHER plekhg5a GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000008563 (1)
  • Ensembl(GRCz11):ENSDARG00000025902 (2)
    • ORTHOLOGY for plekhg5a (Chr: 11)
    CITATIONS (23)