ZFIN ID: ZDB-GENE-060503-693
Gene Name: lysyl oxidase-like 1
Gene Symbol: loxl1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:ch211-238c15.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein-lysine 6-oxidase activity; involved in notochord development; predicted to localize to the extracellular space; orthologous to human LOXL1 (lysyl oxidase like 1).
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027977Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1005 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa5916 Point Mutation Unknown Splice Site ENU
    sa6538 Point Mutation Unknown Premature Stop ENU
    sa16620 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23390 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36735 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36736 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44900 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 5 from Gansner et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH loxl1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    exfoliation syndrome {Exfoliation syndrome, susceptibility to} 177650
    DISEASE ASSOCIATED WITH loxl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process notochord development (more)
    Molecular Function copper ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001695 (1)
  • InterPro:IPR019828 (1)
  • PROSITE:PS00926 (1)
  • Pfam:PF01186 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA loxl1-201 (1) 6757
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM loxl1 No data available
    MARKER RELATIONSHIPS
    loxl1Contained in: [BAC] CH211-238C15 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001043325 (1) 1737bp
    Genomic GenBank:CR762435 (1) 157544bp
    Select Tool
    Polypeptide UniProtKB:A6MH29 (1) 526aa
    Sequence Clusters UniGene:87397 (1)
    Sequence Information (all 14)
    OTHER loxl1 GENE PAGES
  • Alliance (1)
  • Gene:560115 (1)
  • VEGA:OTTDARG00000017806 (1)
  • Ensembl(GRCz11):ENSDARG00000054451 (2)
  • ORTHOLOGY for loxl1 (Chr: 18)
    CITATIONS (21)