ZFIN ID: ZDB-GENE-060503-681
Gene Name: protein phosphatase 1, regulatory subunit 8a
Gene Symbol: ppp1r8a    Nomenclature History

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Previous Names: ppp1r8, si:ch211-206a7.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have mRNA binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation and production of miRNAs involved in gene silencing by miRNA. Predicted to localize to the nuclear speck. Orthologous to human PPP1R8 (protein phosphatase 1 regulatory subunit 8).
Genome Resources: Alliance (1),  Gene:566830 (1),  Ensembl(GRCz11):ENSDARG00000007186 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16598 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ppp1r8a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp1r8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component nuclear speck (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000253 Forkhead-associated (FHA) domain
    Homologous_superfamily IPR008984 SMAD/FHA domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp1r8a-201 (1)    Ensembl 1282
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp1r8a No data available
    MARKER RELATIONSHIPS
    ppp1r8a Contained in: [BAC] CH211-206A7 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100952 (1)
    Genomic GenBank:AL954143 (1) 167732 bp
    Select Tool
    Polypeptide UniProtKB:A5PF58 (1) 351 aa
    Sequence Information (all 5)
    ORTHOLOGY for ppp1r8a ( Chr: 19 )
    CITATIONS (15)