Gene

nfatc1

ID
ZDB-GENE-060503-677
Name
nuclear factor of activated T cells 1
Symbol
nfatc1 Nomenclature History
Previous Names
  • si:ch211-198c22.2
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Involved in lymphangiogenesis and response to mechanical stimulus. Predicted to localize to transcription regulator complex. Is expressed in several structures, including adaxial cell; heart; olfactory system; scale; and tail bud. Orthologous to human NFATC1 (nuclear factor of activated T cells 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nfatc1 Human Ortholog
No data available
Associated With nfatc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002909 IPT domain
Domain IPR011539 Rel homology domain (RHD), DNA-binding domain
Domain IPR032397 Rel homology dimerisation domain
Family IPR008366 Nuclear factor of activated T cells (NFAT)
Family IPR015647 Nuclear factor of activated T-cells 1
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR037059 Rel homology domain (RHD), DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain Nuclear factor of activated T-cells 1 Nuclear factor of activated T cells (NFAT) p53-like transcription factor, DNA-binding Rel homology dimerisation domain Rel homology domain (RHD), DNA-binding domain Rel homology domain (RHD), DNA-binding domain superfamily
UniProtKB:F1QUZ9 867
UniProtKB:Q19AW4 867
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations