ZFIN ID: ZDB-GENE-060503-677
Gene Name: nuclear factor of activated T cells 1
Gene Symbol: nfatc1    Nomenclature History

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Previous Name: si:ch211-198c22.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in response to mechanical stimulus. Predicted to localize to cytosol; nucleus; and transcription regulator complex. Is expressed in several structures, including adaxial cell; heart; olfactory system; scale; and tail bud. Orthologous to human NFATC1 (nuclear factor of activated T cells 1).
Genome Resources: Alliance (1),  Gene:568315 (1),  Ensembl(GRCz11):ENSDARG00000036168 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020672Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36826 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39244 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • y617 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nfatc1 1
    MO1-nfatc1 N/A 1
    MO2-nfatc1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nfatc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nfatc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to mechanical stimulus (more)
    Cellular Component cytosol (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nfatc1-201 (1)    Ensembl 3905
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM nfatc1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    TgBAC(nfatc1:GAL4FF) nfatc1 GAL4FF Danio rerio 1 5
    MARKER RELATIONSHIPS
    nfatc1 Contained in: [BAC] CH73-196L6 (1), CH73-309F6 (1), CH211-198C22 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045159 (1) 2991 nt
    Genomic GenBank:BX855612 (1) 212866 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QUZ9 (1) 867 aa
    Sequence Information (all 13)
    ORTHOLOGY for nfatc1 ( Chr: 19 )
    CITATIONS (41)