Gene

rspo2

ID
ZDB-GENE-060503-667
Name
R-spondin 2
Symbol
rspo2 Nomenclature History
Previous Names
  • si:ch211-149p10.1
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Involved in fin development and skeletal system development. Is expressed in several structures, including brain; fin; forebrain midbrain boundary neural rod; pectoral fin bud; and posterior lateral line ganglion. Orthologous to human RSPO2 (R-spondin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Tatsumi et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rspo2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
tetraamelia syndrome 2 Alliance Tetraamelia syndrome 2 618021
?Humerofemoral hypoplasia with radiotibial ray deficiency 618022
Associated With rspo2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR043601 R-spondin, Fu-CRD domain
Family IPR042993 R-spondin-2/4
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Repeat IPR006212 Furin-like repeat
Domain Details Per Protein
Protein Length Furin-like repeat Growth factor receptor cysteine-rich domain superfamily R-spondin-2/4 R-spondin, Fu-CRD domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:F1Q5C9
UniProtKB:F1QG95 210
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations