ZFIN ID: ZDB-GENE-060503-62
Gene Name: anoctamin 2
Gene Symbol: ano2
Previous Names: si:dkey-224k5.2, tmem16b (1)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
  dorsal habenular nucleus
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31371 Point Mutation Unknown Unknown ENU
sa33366 Point Mutation Unknown Unknown ENU
sa33367 Point Mutation Unknown Unknown ENU
sa40208 Point Mutation Unknown Unknown ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ano2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process chloride transport (more)
Cellular Component integral component of membrane (more)
Molecular Function intracellular calcium activated chloride channel activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007632 (1)
  • InterPro:IPR031288 (1)
  • InterPro:IPR032394 (1)
  • Pfam:PF04547 (1)
  • Pfam:PF16178 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ano2-001 (1) 6472
    ncRNA ano2-002 (1) 1513
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ano2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ano2Contained in: [BAC] CH211-60D22 (1) (order this), DKEY-224K5 (1) (order this)
    ano2Encodes: [cDNA] MGC:171498 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001327858 (1) 4287bp
    Genomic GenBank:CU468826 (1) 180804bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IKC5 (1) 998aa
    Sequence Clusters UniGene:114611 (1)
    Sequence Information (all 17)
    OTHER ano2 GENE PAGES
  • Gene:566373 (1)
  • VEGA:OTTDARG00000014531 (1)
  • Ensembl(GRCz10):ENSDARG00000101363 (1)
  • ORTHOLOGY for ano2 (Chr: 4)
    Species Symbol Chromosome Accession # Evidence
    Human ANO2 12
  • Gene:57101
  • OMIM:610109
  • HGNC:1183
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (16)