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ZIRC
ZFIN ID: ZDB-GENE-060503-577
Gene Name: si:ch211-15p9.2
Gene Symbol: si:ch211-15p9.2    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have [pyruvate dehydrogenase (lipoamide)] phosphatase activity and magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehyrogenase phosphatase catalytic subunit 1).
Genome Resources: Alliance (1), Gene:562650 (1), Ensembl(GRCz11):ENSDARG00000062241 (1)

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1211 Point Mutation Unknown Premature Stop ENU
sa30658 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH si:ch211-15p9.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH si:ch211-15p9.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein dephosphorylation (more)
    Cellular Component mitochondrion (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:ch211-15p9.2-201 (1)    Ensembl 1746
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM si:ch211-15p9.2No data available
    MARKER RELATIONSHIPS
    si:ch211-15p9.2Contained in: [BAC] CH211-15P9 (1) (order this)
    si:ch211-15p9.2Encodes: [cDNA] MGC:162755 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044990 (1) 1789bp
    Genomic GenBank:BX001056 (1) 150229bp
    Select Tool
    Polypeptide UniProtKB:A4IGD9 (1) 505aa
    Sequence Clusters UniGene:74140 (1)
    Sequence Information (all 10)
    ORTHOLOGY for si:ch211-15p9.2 (Chr: 11)
    CITATIONS (15)