ZFIN ID: ZDB-GENE-060503-544
Gene Name: solute carrier family 26 member 4
Gene Symbol: slc26a4
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-31f5.9

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have transport; involved in anion homeostasis, chloride transport, and response to salt stress; predicted to localize to the integral component of membrane; orthologous to human SLC26A4  ...
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20257 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc26a4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive nonsyndromic deafness 4 Deafness, autosomal recessive 4, with enlarged vestibular aqueduct 600791
    Pendred Syndrome Pendred syndrome 274600
    DISEASE ASSOCIATED WITH slc26a4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anion homeostasis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function secondary active sulfate transmembrane transporter activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001902 (1)
  • InterPro:IPR002645 (1)
  • InterPro:IPR011547 (1)
  • InterPro:IPR018045 (1)
  • InterPro:IPR030285 (1)
  • InterPro:IPR036513 (1)
  • PROSITE:PS01130 (1)
  • PROSITE:PS50801 (1)
  • Pfam:PF00916 (1)
  • Pfam:PF01740 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc26a4-202 (1) 2232
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc26a4 No data available
    MARKER RELATIONSHIPS
    slc26a4Contained in: [BAC] DKEY-31F5 (1) (order this), DKEYP-15G12 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001165915 (1) 2390bp
    Genomic GenBank:BX649534 (1) 205347bp Blast at MegaBLAST
    Polypeptide UniProtKB:C8XTB7 (1) 760aa
    Sequence Clusters UniGene:155439 (1)
    Sequence Information (all 15)
    OTHER slc26a4 GENE PAGES
  • Alliance (1)
  • Gene:563818 (1)
  • VEGA:OTTDARG00000016612 (1)
  • Ensembl(GRCz11):ENSDARG00000069431 (2)
  • ORTHOLOGY for slc26a4 (Chr: 4)
    CITATIONS (24)