Gene
vps45
- ID
- ZDB-GENE-060503-526
- Name
- vacuolar protein sorting 45 homolog
- Symbol
- vps45 Nomenclature History
- Previous Names
-
- si:dkey-200h23.3
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in regulation of lens fiber cell differentiation. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| severe congenital neutropenia 5 | Alliance | Neutropenia, severe congenital, 5, autosomal recessive | 615285 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sec1-like, domain 1 | Sec1-like, domain 2 | Sec1-like, domain 3a | Sec1-like protein | Sec1-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A8E7N5
|
568 |
Interactions and Pathways
No data available
Plasmids
No data available