Gene

vps45

ID
ZDB-GENE-060503-526
Name
vacuolar protein sorting 45 homolog
Symbol
vps45 Nomenclature History
Previous Names
  • si:dkey-200h23.3
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Involved in regulation of lens fiber cell differentiation. Predicted to localize to Golgi membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps45 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neutropenia, severe congenital, 5, autosomal recessive 615285
Associated With vps45 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001619 Sec1-like protein
Homologous_superfamily IPR027482 Sec1-like, domain 2
Homologous_superfamily IPR036045 Sec1-like superfamily
Domain Details Per Protein
Protein Length Sec1-like, domain 2 Sec1-like protein Sec1-like superfamily
UniProtKB:A8E7N5 568
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations