Gene

gabbr1b

ID
ZDB-GENE-060503-5
Name
gamma-aminobutyric acid (GABA) B receptor, 1b
Symbol
gabbr1b Nomenclature History
Previous Names
  • gabbr1.2 (1)
  • hbog (1)
  • humphrey bogart (1)
  • si:ch211-127d20.2
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have G protein-coupled GABA receptor activity. Involved in behavioral response to nicotine. Predicted to localize to G protein-coupled receptor heterodimeric complex. Is expressed in central nervous system; eye; female organism; and male organism. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gabbr1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with language delay and variable cognitive abnormalities 620502
Associated With gabbr1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR001828 Receptor, ligand binding region
Domain IPR017978 GPCR family 3, C-terminal
Family IPR002455 GPCR family 3, GABA-B receptor
Family IPR002456 GPCR family 3, gamma-aminobutyric acid receptor, type B1
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Domain Details Per Protein
Protein Length GPCR family 3, C-terminal GPCR family 3, GABA-B receptor GPCR family 3, gamma-aminobutyric acid receptor, type B1 Periplasmic binding protein-like I Receptor, ligand binding region Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:F1QAJ3 993
UniProtKB:A0A8M2BHH0 994
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations