ZFIN ID: ZDB-GENE-060503-38
Gene Name: tissue factor pathway inhibitor 2
Gene Symbol: tfpi2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:ch211-262k23.2 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in several processes, including heart development; regulation of hemopoiesis; and sarcomere organization. Predicted to localize to extracellular space. Is expressed in brain; eye; heart; liver; and ovary. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2).
Genome Resources: Alliance (1),  Gene:560339 (1),  Ensembl(GRCz11):ENSDARG00000061351 (1)
GENE EXPRESSION
All Expression Data: 2 figures from Zhang et al., 2013
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-tfpi2 N/A 2
MO2-tfpi2 N/A 2
DISEASE ASSOCIATED WITH tfpi2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tfpi2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process central nervous system development (more)
Cellular Component extracellular region (more)
Molecular Function peptidase inhibitor activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tfpi2-201 (1)    Ensembl 1665
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tfpi2 No data available
MARKER RELATIONSHIPS
tfpi2 Contained in: [BAC] CH211-120E1 (1), CH211-262K23 (1)
tfpi2 Encodes: [cDNA] MGC:153805 (1), MGC:191502 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001040096 (1) 1666 nt
Genomic GenBank:BX537314 (1) 168538 nt
Select Tool
Polypeptide UniProtKB:Q1WCN6 (1) 233 aa
Sequence Information (all 18)
ORTHOLOGY for tfpi2 ( Chr: 19 )
CITATIONS (22)