Gene

tfpi2

ID
ZDB-GENE-060503-38
Name
tissue factor pathway inhibitor 2
Symbol
tfpi2 Nomenclature History
Previous Names
  • si:ch211-262k23.2 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including heart development; regulation of hemopoiesis; and sarcomere organization. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; eye; heart; liver; and ovary. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Zhang et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfpi2 Human Ortholog
No data available
Associated With tfpi2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Domain IPR002223 Pancreatic trypsin inhibitor Kunitz domain
Family IPR008296 Tissue factor pathway inhibitor-like
Family IPR029860 Tissue factor pathway inhibitor 2
Homologous_superfamily IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
Domain Details Per Protein
Protein Length Pancreatic trypsin inhibitor Kunitz domain Pancreatic trypsin inhibitor Kunitz domain superfamily Proteinase inhibitor I2, Kunitz, conserved site Tissue factor pathway inhibitor 2 Tissue factor pathway inhibitor-like
UniProtKB:Q1WCN6 233
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations