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ZIRC
ZFIN ID: ZDB-GENE-060503-376
Gene Name: lysine (K)-specific methyltransferase 2Ba
Gene Symbol: kmt2ba    Nomenclature History

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Previous Names: mll4a, si:rp71-15k1.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have histone methyltransferase activity (H3-K4 specific). Predicted to be involved in histone H3-K4 methylation and positive regulation of transcription, DNA-templated. Predicted to localize to the histone methyltransferase complex. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; dystonia; and hepatocellular carcinoma. Orthologous to human KMT2B (lysine methyltransferase 2B).
Genome Resources: Alliance (1),  Gene:560856 (1),  Ensembl(GRCz11):ENSDARG00000062962 (2)
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH kmt2ba HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Dystonia 28, childhood-onset 617284
DISEASE ASSOCIATED WITH kmt2ba VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process histone H3-K4 methylation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (nt) Analysis
antisense ottdart00000059906 (1) 684
mRNA kmt2ba-201 (1)    Ensembl 9950
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM kmt2ba No data available
MARKER RELATIONSHIPS
kmt2ba Contained in: [BAC] CH211-130O18 (1) (order this), RP71-15K1 (1) (order this)
kmt2ba Encodes: [EST] wz12125 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_684255 (1) 10149 bp
Genomic GenBank:CR391915 (1) 77634 bp
Select Tool
Polypeptide UniProtKB:A0A2R8Q4Z6 (1) 2945 aa
Sequence Clusters UniGene:160187 (1)
Sequence Information (all 33)
ORTHOLOGY for kmt2ba ( Chr: 19 )
CITATIONS (27)