ZFIN ID: ZDB-GENE-060503-372
Gene Name: paired box 1b
Gene Symbol: pax1b    Nomenclature History

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Previous Name: si:dkeyp-50f5.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Involved in embryonic skeletal system development and pectoral fin development. Predicted to localize to nucleus. Is expressed in axial blood vessel; fin bud; notochord; pharynx; and somite. Human ortholog(s) of this gene implicated in branchiootorenal syndrome. Orthologous to human PAX1 (paired box 1).
Genome Resources: Alliance (1),  Gene:572108 (1),  Ensembl(GRCz11):ENSDARG00000073814 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43535 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pax1b N/A 2
    MO2-pax1b N/A 1
    DISEASE ASSOCIATED WITH pax1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Otofaciocervical syndrome 2 615560
    DISEASE ASSOCIATED WITH pax1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic skeletal system development (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pax1b-201 (1)    Ensembl 1659
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pax1b No data available
    MARKER RELATIONSHIPS
    pax1b Contained in: [BAC] DKEYP-50F5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_695785 (1)
    Genomic GenBank:BX663521 (1) 179633 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8PYI0 (1) 353 aa
    Sequence Information (all 11)
    ORTHOLOGY for pax1b ( Chr: 20 )
    CITATIONS (21)