ZFIN ID: ZDB-GENE-060503-348
Gene Name: VPS8 subunit of CORVET complex
Gene Symbol: vps8    Nomenclature History

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Previous Names: im:7166005, si:dkey-24b15.1 (1), zgc:158695 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Orthologous to human VPS8 (VPS8 subunit of CORVET complex).
Genome Resources: Alliance (1),  Gene:791134 (1),  Ensembl(GRCz11):ENSDARG00000060477 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7166005]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011002Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021109Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028124Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19514 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko575a Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-vps8 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vps8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vps8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular protein transport (more)
    Cellular Component cellular_component (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR017986 WD40-repeat-containing domain
    Domain IPR025941 Vacuolar protein sorting-associated protein 8, central domain
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
    Repeat IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
    Repeat IPR001680 WD40 repeat
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vps8-201 (1)    Ensembl 1528
    vps8-202 (1)    Ensembl 687
    vps8-203 (1)    Ensembl 4399
    vps8-204 (1)    Ensembl 830
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vps8 No data available
    MARKER RELATIONSHIPS
    vps8 Contained in: [BAC] CH73-115F13 (1), CH211-168J2 (1), CH211-236L15 (1), DKEY-24B15 (1) (order this)
    vps8 Encodes: [EST] IMAGE:7166005 (1)
    [cDNA] MGC:158695 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001080616 (1) 1540 nt
    Genomic GenBank:BX088533 265699 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QQ05 (1) 1412 aa
    Sequence Information (all 30)
    ORTHOLOGY for vps8 ( Chr: 1 )
    CITATIONS (27)