Gene

tm6sf2

ID
ZDB-GENE-060503-338
Name
transmembrane 6 superfamily member 2
Symbol
tm6sf2 Nomenclature History
Previous Names
  • si:dkey-19f23.3
  • zgc:158825
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Involved in lipid homeostasis and regulation of response to endoplasmic reticulum stress. Predicted to localize to endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in intestine; liver; and posterior intestine. Used to study fatty liver disease. Orthologous to several human genes including TM6SF2 (transmembrane 6 superfamily member 2).
Genome Resources
Note
None
Expression
All Expression Data
from O'Hare et al., 2017
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from O'Hare et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tm6sf2 Human Ortholog
No data available
Associated With tm6sf2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR033118 EXPERA domain
Domain Details Per Protein
Protein Length EXPERA domain
UniProtKB:A1L2E0 374
UniProtKB:Q1LV23 374
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations