Gene

syt2a

ID
ZDB-GENE-060503-315
Name
synaptotagmin IIa
Symbol
syt2a Nomenclature History
Previous Names
  • si:ch211-236j4.1 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and synaptic vesicle cycle. Predicted to localize to axon; plasma membrane; and secretory vesicle. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Orthologous to human SYT2 (synaptotagmin 2).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 2 from Kiesow et al., 2015
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With syt2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital myasthenic syndrome 7 Alliance Myasthenic syndrome, congenital, 7, presynaptic 616040
Associated With syt2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR001565 Synaptotagmin
Family IPR015428 Synaptotagmin 1
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily Synaptotagmin Synaptotagmin 1
UniProtKB:F1R5C0 430
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations