ZFIN ID: ZDB-GENE-060503-315 |
Gene Name: | synaptotagmin IIa | ||||||
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Gene Symbol: | syt2a Nomenclature History | ||||||
Previous Name: | si:ch211-236j4.1 (1) | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 23 Mapping Details/Browsers | ||||||
Description: | Predicted to have several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and synaptic vesicle cycle. Predicted to localize to the axon; plasma membrane; and secretory vesicle. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Orthologous to human SYT2 (synaptotagmin 2). | ||||||
Genome Resources: | Alliance (1), Gene:567877 (1), Ensembl(GRCz11):ENSDARG00000025206 (1) |
All Expression Data: | Fig. 2 from Kiesow et al., 2015 |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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la011005Tg | Transgenic Insertion | Unknown | Unknown | DNA |
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la022794Tg | Transgenic Insertion | Unknown | Unknown | DNA | |
la022795Tg | Transgenic Insertion | Unknown | Unknown | DNA |
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Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
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congenital myasthenic syndrome 7 | Alliance | Myasthenic syndrome, congenital, 7, presynaptic | 616040 |
Ontology | GO Term |
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Biological Process | neurotransmitter secretion (more) |
Cellular Component | integral component of membrane (more) |
Molecular Function | calcium-dependent phospholipid binding (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
syt2a-202
(1)
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1951 |
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ncRNA | syt2a-002 (1) | 659 |
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Browsers: NCBI, Ensembl, ZFIN |
syt2a Contained in: | [BAC] CH211-212J22 (1) (order this), CH211-236J4 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:XM_005174112 (1) |
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Genomic | GenBank:BX323087 (1) | 192603 bp | |
Polypeptide | UniProtKB:F1R5C0 (1) | 430 aa |
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Sequence Clusters | UniGene:120327 (1) |