ZFIN ID: ZDB-GENE-060503-314
Gene Name: C-reactive protein 1
Gene Symbol: crp1    Nomenclature History

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Previous Name: si:ch211-234p6.14

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Predicted to localize to extracellular region. Is expressed in ovary and testis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune hypersensitivity disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Orthologous to human CRP (C-reactive protein) and APCS (amyloid P component, serum).
Genome Resources: Alliance (1),  Gene:570508 (1),  Ensembl(GRCz11):ENSDARG00000071454 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Sheng et al., 2015
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3267 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15702 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH crp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component extracellular region (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA crp1-201 (1)    Ensembl 678
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM crp1 No data available
    MARKER RELATIONSHIPS
    crp1 Contained in: [BAC] CH211-234P6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_693995 (1)
    Genomic GenBank:BX001030 (1) 156560 nt
    Select Tool
    Polypeptide UniProtKB:A3KPG7 (1) 225 aa
    Sequence Information (all 4)
    ORTHOLOGY for crp1 ( Chr: 24 )
    CITATIONS (22)