ZFIN Gene: magi3b

ZFIN ID: ZDB-GENE-060503-301

ZFIN ID: ZDB-GENE-060503-301

Gene Name:

membrane associated guanylate kinase, WW and PDZ domain containing 3b

Gene Symbol:

magi3b Nomenclature History

Previous Name:

si:ch211-1l10.1 (1)

Gene Type:

protein_coding_gene

Location:

Description:

Involved in cilium assembly. Localizes to cytoplasm.

Genome Resources:

Alliance (1), Ensembl(GRCz11):ENSDARG00000025974 (2)

GENE EXPRESSION
All Expression Data:	Fig. S3 from Choksi et al., 2014
Wild-type Stages, Structures:	Segmentation:26+ somites (22.0h-24.0h) to Segmentation:26+ somites (22.0h-24.0h)
	whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa15982	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa20807	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa20808	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa20809	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa31537	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa31538	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa40785	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa40786	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa44644	Point Mutation	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
MO1-magi3b	N/A	1

PHENOTYPE

Data:	2 figures from Choksi et al., 2014
Observed in:	determination of left/right symmetry otolith pronephric duct cilium ventricular system whole organism anterior-posterior axis

DISEASE ASSOCIATED WITH magi3b HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH magi3b VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cilium assembly (more)
Cellular Component	cytoplasm (more)

GO Terms (all 5)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	magi3b-202 (1)	5479	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM magi3b No data available

MARKER RELATIONSHIPS

magi3b Contained in:

[BAC] CH211-1L10 (1), DKEY-42O15 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
Genomic	GenBank:AL929512 (1)	197232 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:E9QIL2 (1)	1114 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

ORTHOLOGY for magi3b ( Chr: 6 )

CITATIONS (14)