Gene
wdr62
- ID
- ZDB-GENE-060503-291
- Name
- WD repeat domain 62
- Symbol
- wdr62 Nomenclature History
- Previous Names
-
- fa11h05
- fb33e12
- si:ch211-152c12.2
- wu:fa11h05
- wu:fb33e12
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Used to study microcephaly. Human ortholog(s) of this gene implicated in intellectual disability; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 2 with or without cortical malformations. Orthologous to human WDR62 (WD repeat domain 62).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 2 with or without cortical malformations | Alliance | Microcephaly 2, primary, autosomal recessive, with or without cortical malformations | 604317 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| microcephaly | WT + MO1-wdr62 | standard conditions | Novorol et al., 2013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Quinoprotein alcohol dehydrogenase-like superfamily | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:F6NPK9
|
1493 | ||||
|
UniProtKB:A0A8M2BH37
|
1492 | ||||
|
UniProtKB:A0A286YBK5
|
1519 | ||||
|
UniProtKB:A0A8M2BGZ4
|
1518 |
Interactions and Pathways
No data available
Plasmids
No data available