ZFIN is now using GRCz12tu for Genomic Data
Gene
dennd4a
- ID
- ZDB-GENE-060503-285
- Name
- DENN/MADD domain containing 4A
- Symbol
- dennd4a Nomenclature History
- Previous Names
-
- si:ch211-117i10.9
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rab protein signal transduction. Predicted to be active in cytoplasmic vesicle. Orthologous to human DENND4A (DENN domain containing 4A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001194 | cDENN domain |
| Domain | IPR005112 | dDENN domain |
| Domain | IPR005113 | uDENN domain |
| Domain | IPR023341 | MABP domain |
| Domain | IPR037516 | Tripartite DENN domain |
| Family | IPR051696 | DENN Domain-Containing GEFs |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR043153 | DENN domain, C-terminal lobe |
| Repeat | IPR002885 | Pentatricopeptide repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | cDENN domain | dDENN domain | DENN Domain-Containing GEFs | DENN domain, C-terminal lobe | MABP domain | Pentatricopeptide repeat | Tetratricopeptide-like helical domain superfamily | Tripartite DENN domain | uDENN domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B5K2 | InterPro | 1723 | |||||||||
| UniProtKB:A0A2R8Q0K6 | InterPro | 1715 | |||||||||
| UniProtKB:Q1LV52 | InterPro | 1674 | |||||||||
| UniProtKB:F1QRM3 | InterPro | 1714 | |||||||||
| UniProtKB:A0A286Y972 | InterPro | 1724 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dennd4a-201
(1)
|
Ensembl | 5,427 nt | ||
| mRNA |
dennd4a-202
(1)
|
Ensembl | 5,312 nt | ||
| mRNA |
dennd4a-203
(1)
|
Ensembl | 5,719 nt | ||
| mRNA |
dennd4a-204
(1)
|
Ensembl | 5,692 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers