ZFIN ID: ZDB-GENE-060503-240
Gene Name: tubulointerstitial nephritis antigen-like 1
Gene Symbol: tinagl1    Nomenclature History

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Previous Names: LCN7 (1), lipocalin-7 (1), si:dkey-158b13.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have cysteine-type peptidase activity and peptidase inhibitor activity. Involved in embryonic viscerocranium morphogenesis and sprouting angiogenesis. Predicted to localize to extracellular space and lysosome. Orthologous to human TINAGL1 (tubulointerstitial nephritis antigen like 1).
Genome Resources: Alliance (1),  Gene:562116 (1),  Ensembl(GRCz11):ENSDARG00000061231 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010796Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la020838Tg Transgenic Insertion Unknown Unknown DNA
    sa11655 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tinagl1 N/A 2
    MO2-tinagl1 N/A 1
    MO3-tinagl1 N/A 1
    MO4-tinagl1 N/A 1
    DISEASE ASSOCIATED WITH tinagl1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tinagl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic viscerocranium morphogenesis (more)
    Cellular Component extracellular space (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tinagl1-201 (1)    Ensembl 1759
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tinagl1 No data available
    MARKER RELATIONSHIPS
    tinagl1 Contained in: [BAC] DKEY-158B13 (1) (order this)
    tinagl1 Encodes: [cDNA] MGC:161996 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044977 (1) 1780 nt
    Genomic GenBank:BX950864 (1) 185429 nt
    Select Tool
    Polypeptide UniProtKB:A3KNG7 (1) 471 aa
    Sequence Information (all 12)
    ORTHOLOGY for tinagl1 ( Chr: 19 )
    CITATIONS (24)