ZFIN ID: ZDB-GENE-060503-218
Gene Name: fibronectin type III and SPRY domain containing 1
Gene Symbol: fsd1    Nomenclature History

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Previous Name: si:ch211-232d19.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Involved in Notch signaling pathway; cilium assembly; and hematopoietic progenitor cell differentiation. Predicted to localize to several cellular components, including cleavage furrow; microtubule cytoskeleton; and nucleus. Orthologous to human FSD1 (fibronectin type III and SPRY domain containing 1).
Genome Resources: Alliance (1),  Gene:566722 (1),  Ensembl(GRCz11):ENSDARG00000062017 (2)
GENE EXPRESSION
All Expression Data: Fig. S3 from Liu et al., 2019
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ioz104 Insertion Unknown Unknown CRISPR
la016281Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026379Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7611 Point Mutation Unknown Missense ENU
    sa15589 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fsd1 2
    MO1-fsd1 N/A 2
    MO2-fsd1 N/A 2
    DISEASE ASSOCIATED WITH fsd1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fsd1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component cleavage furrow (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fsd1 No data available
    MARKER RELATIONSHIPS
    fsd1 Contained in: [BAC] CH211-232D19 (1)
    fsd1 Encodes: [cDNA] MGC:193935 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045117 (1) 2131 nt
    Genomic GenBank:BX247907 169530 nt
    Select Tool
    Polypeptide UniProtKB:B3DG96 (1) 495 aa
    Sequence Information (all 12)
    ORTHOLOGY for fsd1 ( Chr: 8 )
    CITATIONS (26)