ZFIN ID: ZDB-GENE-060503-193
Gene Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Gene Symbol: hcn3    Nomenclature History

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Previous Name: si:ch211-130o18.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transport and transmembrane transport. Predicted to localize to the integral component of membrane. Orthologous to human HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3).
Genome Resources: Alliance (1),  Gene:560709 (1),  Ensembl(GRCz11):ENSDARG00000027192 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6545 Point Mutation Unknown Splice Site ENU
sa25085 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hcn3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hcn3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component integral component of membrane (more)
Molecular Function ion channel activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000595 Cyclic nucleotide-binding domain
Family IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG
Domain IPR005821 Ion transport domain
Domain IPR013621 Ion transport N-terminal
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hcn3-201 (1)    Ensembl 2517
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hcn3 No data available
MARKER RELATIONSHIPS
hcn3 Contained in: [BAC] CH211-130O18 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_684105 (1) 1920 bp
Genomic GenBank:CR391915 (1) 77634 bp
Select Tool
Polypeptide UniProtKB:F6NQL8 (1) 639 aa
Sequence Information (all 6)
ORTHOLOGY for hcn3 ( Chr: 19 )
CITATIONS (17)