Gene

pias2

ID
ZDB-GENE-060424-1
Name
protein inhibitor of activated STAT, 2
Symbol
pias2 Nomenclature History
Previous Names
  • piasx (1)
  • wu:fi05f09
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II transcription factor binding activity; SUMO ligase activity; and transcription coregulator activity. Predicted to be involved in protein sumoylation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pias2 Human Ortholog
No data available
Associated With pias2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003034 SAP domain
Domain IPR004181 Zinc finger, MIZ-type
Domain IPR023321 PINIT domain
Family IPR027228 E3 SUMO-protein ligase PIAS2
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036361 SAP domain superfamily
Homologous_superfamily IPR038654 PINIT domain superfamily
Domain Details Per Protein
Protein Length E3 SUMO-protein ligase PIAS2 PINIT domain PINIT domain superfamily SAP domain SAP domain superfamily Zinc finger, MIZ-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A2R8PZZ8 614
UniProtKB:X1WFJ1 615
UniProtKB:S6CLU6 614
UniProtKB:A0A2R8PXS2 623
UniProtKB:A2CE49 155
UniProtKB:A2CE48 623
UniProtKB:A2CE50 202
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations