Gene

numb

ID
ZDB-GENE-060422-1
Name
NUMB endocytic adaptor protein
Symbol
numb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have cadherin binding activity. Involved in determination of left/right symmetry and primitive erythrocyte differentiation. Localizes to basolateral plasma membrane and cytoplasm. Is expressed in brain; digestive system; immature eye; neural tube; and neuromast. Orthologous to human NUMB (NUMB endocytic adaptor protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With numb Human Ortholog
No data available
Associated With numb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006020 PTB/PI domain
Domain IPR010449 NUMB domain
Family IPR016698 Numb/numb-like
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length NUMB domain Numb/numb-like PH-like domain superfamily PTB/PI domain
UniProtKB:B3DG87 680
UniProtKB:F1QPD8 680
UniProtKB:Q1XD15 680
UniProtKB:Q1XD14 669
UniProtKB:X1WE89 208
UniProtKB:F1RDZ7 669
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations