Gene

f9b

ID
ZDB-GENE-060421-7346
Name
coagulation factor IXb
Symbol
f9b Nomenclature History
Previous Names
  • zgc:136807
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in blood coagulation and proteolysis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in X-linked thrombophilia due to factor IX defect; hemophilia B; and warfarin sensitivity. Orthologous to human F9 (coagulation factor IX).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With f9b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hemophilia B Alliance Hemophilia B 306900
X-linked thrombophilia due to factor IX defect Alliance Thrombophilia, X-linked, due to factor IX defect 300807
X-linked thrombophilia due to factor IX defect Alliance {Deep venous thrombosis, protection against} 300807
X-linked warfarin sensitivity Alliance {Warfarin sensitivity} 301052
Associated With f9b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
Domain IPR000742 EGF-like domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR001881 EGF-like calcium-binding domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z
Family IPR035694 Coagulation factor IX
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR017857 Coagulation factor-like, Gla domain superfamily
Homologous_superfamily IPR035972 Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Coagulation factor IX Coagulation factor-like, Gla domain superfamily EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Gamma-carboxyglutamic acid-rich (GLA) domain Gamma-carboxyglutamic acid-rich (GLA) domain superfamily Peptidase S1A, chymotrypsin family Peptidase S1A, coagulation factor VII/IX/X/C/Z Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site
UniProtKB:Q1RLV2 507
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations