ZFIN ID: ZDB-GENE-060421-6989
Gene Name: BRCA1-associated ATM activator 1
Gene Symbol: brat1    Nomenclature History

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Previous Name: zgc:136845

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to be involved in cellular response to DNA damage stimulus; positive regulation of protein phosphorylation; and response to ionizing radiation. Predicted to localize to the cytoplasm and nucleus. Orthologous to human BRAT1 (BRCA1 associated ATM activator 1).
Genome Resources: Alliance (1),  Gene:678547 (1),  Ensembl(GRCz11):ENSDARG00000062585 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31195 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko244a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko244b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-brat1 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH brat1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Neurodevelopmental disorder with cerebellar atrophy and with or without seizures 618056
    Rigidity and multifocal seizure syndrome, lethal neonatal 614498
    DISEASE ASSOCIATED WITH brat1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to DNA damage stimulus (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Homologous_superfamily IPR016024 Armadillo-type fold
    Family IPR038904 BRCA1-associated ATM activator 1
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA brat1-201 (1)    Ensembl 2629
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM brat1 No data available
    MARKER RELATIONSHIPS
    brat1 Contained in: [BAC] DKEY-26I13 (1) (order this)
    brat1 Encodes: [cDNA] MGC:136845 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040305 (1) 2635 bp
    Genomic GenBank:BX569798 (1) 215607 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1RLU1 (1) 822 aa
    Sequence Information (all 11)
    ORTHOLOGY for brat1 ( Chr: 1 )
    CITATIONS (18)