Gene

avil

ID
ZDB-GENE-060421-6683
Name
advillin
Symbol
avil Nomenclature History
Previous Names
  • zgc:136857
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to actin cytoskeleton and cytoplasm. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human AVIL (advillin).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With avil Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nephrotic syndrome, type 21 618594
Associated With avil Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003128 Villin headpiece
Domain IPR007123 Gelsolin-like domain
Family IPR007122 Villin/Gelsolin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily IPR036180 Gelsolin-like domain superfamily
Homologous_superfamily IPR036886 Villin headpiece domain superfamily
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin-like domain Gelsolin-like domain superfamily Villin/Gelsolin Villin headpiece Villin headpiece domain superfamily
UniProtKB:Q1RLT7 811
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations