Gene
btr22
- ID
- ZDB-GENE-080402-4
- Name
- bloodthirsty-related gene family, member 22
- Symbol
- btr22 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin-protein transferase activity and zinc ion binding activity. Predicted to act upstream of or within innate immune response and protein ubiquitination. Predicted to be located in cytoplasm. Orthologous to human TRIM29 (tripartite motif containing 29) and TRIM65 (tripartite motif containing 65).
- Genome Resources
- Note
-
The bloodthirsty gene family (ubiquitin ligases) on chromosome 19 has been collapsed into fewer genes in GRCz12Tu compared to GRCz11. As a result, btr20 is no longer annotated in GRCz12Tu and its best alignment is to the annotated location of btr22; therefore, the gene records have been merged.
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003613 | U-box domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR006574 | SPRY-associated |
| Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
| Family | IPR051051 | E3 ubiquitin-protein ligase TRIM/RNF |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | B-box-type zinc finger | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | E3 ubiquitin-protein ligase TRIM/RNF | SPRY-associated | SPRY domain | U-box domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB13A9M6 | InterPro | 520 | |||||||||||||
| UniProtKB:A0AB13AA62 | InterPro | 531 | |||||||||||||
| UniProtKB:A0A0R4IUT0 | InterPro | 544 |
Interactions and Pathways
No data available
Plasmids
No data available