Gene

rtn2a

ID

ZDB-GENE-060420-1

Name

reticulon 2a

Symbol

rtn2a Nomenclature History

Previous Names

rtn2 (1)
zgc:136255

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 12. Is expressed in skeletal muscle. Orthologous to human RTN2 (reticulon 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7162144 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rtn2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spastic paraplegia 12	Alliance	Spastic paraplegia 12, autosomal dominant	604805

Associated With rtn2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003388	Reticulon
Family	IPR046964	Reticulon 1-4

Domain Details Per Protein

Protein	Length	Reticulon	Reticulon 1-4
UniProtKB:A0A8M2B4B6 InterPro	451
UniProtKB:Q4G5K8 InterPro	203
UniProtKB:A0A8M2B494 InterPro	205

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rtn2a-201 (1) Ensembl	Havana	981 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations