ZFIN ID: ZDB-GENE-060418-2
Gene Name: SEC31 homolog B, COPII coat complex component
Gene Symbol: sec31b    Nomenclature History

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Previous Name: sec31l2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Predicted to be involved in COPII-coated vesicle cargo loading; endoplasmic reticulum organization; and intracellular protein transport. Predicted to localize to the COPII vesicle coat and endoplasmic reticulum exit site. Orthologous to human SEC31B (SEC31 homolog B, COPII coat complex component).
Genome Resources: Alliance (1),  Gene:100148383 (1),  Ensembl(GRCz11):ENSDARG00000002916 (2)
GENE EXPRESSION
All Expression Data: Fig. S14 from Niu et al., 2012
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018320Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa873 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10739 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42098 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42099 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sec31b N/A 1
    MO2-sec31b N/A 1
    PHENOTYPE
    Data: Fig. 4 from Niu et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH sec31b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sec31b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport (more)
    Cellular Component COPII vesicle coat (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR019775 WD40 repeat, conserved site
    Domain IPR017986 WD40-repeat-containing domain
    Domain IPR024298 Ancestral coatomer element 1, Sec16/Sec31
    Family IPR040251 Protein transport protein SEC31-like
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
    Repeat IPR001680 WD40 repeat
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sec31b-202 (1)    Ensembl 422
    sec31b-204 (1)    Ensembl 4172
    ncRNA sec31b-003 (1) 758
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sec31b No data available
    MARKER RELATIONSHIPS
    sec31b Contained in: [BAC] CH73-183O18 (1), CH73-300E14 (1)
    [Fosmid] CH1073-448P6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001921546 (1) 3709 nt
    Genomic GenBank:FP102054 (1) 96657 nt
    Select Tool
    Polypeptide UniProtKB:E7F114 (1) 1171 aa
    Sequence Information (all 16)
    ORTHOLOGY for sec31b ( Chr: 12 )
    CITATIONS (23)