ZFIN ID: ZDB-GENE-060405-1
Gene Name: NFS1 cysteine desulfurase
Gene Symbol: nfs1    Nomenclature History

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Previous Names: fb50g03, wu:fb50g03

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have cysteine desulfurase activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to localize to cytosol; mitochondrion; and nucleus. Orthologous to human NFS1 (NFS1 cysteine desulfurase).
Genome Resources: Alliance (1),  Gene:562714 (1),  Ensembl(GRCz11):ENSDARG00000062237 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8913 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30659 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nfs1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nfs1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process [2Fe-2S] cluster assembly (more)
    Cellular Component cytosol (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nfs1-201 (1)    Ensembl 2194
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nfs1 No data available
    MARKER RELATIONSHIPS
    nfs1 Contained in: [BAC] CH211-15P9 (1)
    nfs1 Encodes: [EST] fb50g03
    [cDNA] MGC:162364 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044993 (1) 2166 nt
    Genomic GenBank:BX001056 (1) 150229 nt
    Select Tool
    Polypeptide UniProtKB:Q1LYQ9 (1) 451 aa
    Sequence Information (all 11)
    ORTHOLOGY for nfs1 ( Chr: 11 )
    CITATIONS (24)