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Gene

wnt5a

ID
ZDB-GENE-060328-3
Name
wingless-type MMTV integration site family, member 5a
Symbol
wnt5a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within pronephros development. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in brain; neural crest cell; ovarian follicle; pronephros; and tooth placode. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt5a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant Robinow syndrome 1 Alliance Robinow syndrome, autosomal dominant 1 180700
Associated With wnt5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR026538 Wnt-5a protein
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt-5a protein Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:A7E271 374
UniProtKB:A1BPR0 374
UniProtKB:F1Q8M2 374
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations