ZFIN ID: ZDB-GENE-060322-5
Gene Name: SRY-box transcription factor 1b
Gene Symbol: sox1b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Contributes to DNA-binding transcription factor activity. Involved in positive regulation of DNA-binding transcription factor activity. Predicted to localize to the nuclear transcription factor complex. Is expressed in forebrain; forebrain neural keel; solid lens vesicle; and spinal cord interneuron. Orthologous to human SOX1 (SRY-box transcription factor 1).
Genome Resources: Alliance (1),  Gene:562710 (1),  Ensembl(GRCz11):ENSDARG00000008131 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ka702 Indel Unknown Unknown CRISPR
zko897a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko897b Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sox1b 1
    CRISPR2-sox1b 1
    MO1-sox1a,sox1b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sox1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sox1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of DNA-binding transcription factor activity (more)
    Cellular Component transcription factor complex (more)
    Molecular Function CONTRIBUTES_TO   DNA-binding transcription factor activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR009071 High mobility group box domain
    Family IPR022097 Transcription factor SOX
    Family IPR031268 Transcription factor SOX-1
    Homologous_superfamily IPR036910 High mobility group box domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sox1b-201 (1)    Ensembl 1775
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sox1b No data available
    MARKER RELATIONSHIPS
    sox1b Contained in: [BAC] CH211-138G9
    sox1b Encodes: [cDNA] MGC:172019 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001037662 (1) 1773 nt
    Genomic GenBank:AL929216 (1) 174383 nt
    Select Tool
    Polypeptide UniProtKB:Q2Z1R2 (1) 340 aa
    Sequence Information (all 12)
    ORTHOLOGY for sox1b ( Chr: 1 )
    CITATIONS (27)