ZFIN ID: ZDB-GENE-060312-15
Gene Name: arsenite methyltransferase
Gene Symbol: as3mt    Nomenclature History

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Previous Name: zgc:136933

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have arsenite methyltransferase activity and methylarsonite methyltransferase activity. Predicted to be involved in arsonoacetate metabolic process and toxin metabolic process. Predicted to localize to cytosol. Is expressed in liver. Orthologous to human AS3MT (arsenite methyltransferase).
Genome Resources: Alliance (1),  Gene:664699 (1),  Ensembl(GRCz11):ENSDARG00000027572 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Bambino et al., 2017
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko609a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-as3mt 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH as3mt HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH as3mt VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process arsonoacetate metabolic process (more)
    Cellular Component cytosol (more)
    Molecular Function arsenite methyltransferase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA as3mt-201 (1)    Ensembl 1298
    ncRNA as3mt-002 (1)    Ensembl 1554
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM as3mt No data available
    MARKER RELATIONSHIPS
    as3mt Contained in: [BAC] CH211-176L1 (1)
    as3mt Encodes: [cDNA] MGC:136933 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039839 (1) 1306 nt
    Genomic GenBank:CR759807 (1) 169839 nt
    Select Tool
    Polypeptide UniProtKB:B8JIF1 (1) 377 aa
    Sequence Information (all 11)
    ORTHOLOGY for as3mt ( Chr: 1 )
    CITATIONS (17)