ZFIN ID: ZDB-GENE-060228-7
Gene Name: ras homolog family member H
Gene Symbol: rhoh    Nomenclature History

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Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in regulation of cell differentiation and regulation of cell-cell adhesion. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human RHOH (ras homolog family member H).
Genome Resources: Alliance (1),  Gene:553413 (1),  Ensembl(GRCz11):ENSDARG00000070121 (2)
GENE EXPRESSION
All Expression Data: Fig. 4 from Salas-Vidal et al., 2005
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko449a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko449b Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rhoh 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rhoh HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {?Epidermodysplasia verruciformis, susceptibility to, 4} 618307
    DISEASE ASSOCIATED WITH rhoh VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process small GTPase mediated signal transduction (more)
    Cellular Component cell cortex (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rhoh-201 (1)    Ensembl 588
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rhoh No data available
    MARKER RELATIONSHIPS
    rhoh Contained in: [BAC] DKEY-274K22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001327973 (1)
    Genomic GenBank:CR759875 (1) 216255 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R1D2 (1) 195 aa
    Sequence Information (all 8)
    ORTHOLOGY for rhoh ( Chr: 1 )
    CITATIONS (15)