Gene

corin

ID
ZDB-GENE-060224-3
Name
corin, serine peptidase
Symbol
corin Nomenclature History
Previous Names
  • si:ch1073-76a20.1
  • zmp:0000000798
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have scavenger receptor activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in hypertension and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With corin Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Preeclampsia/eclampsia 5 614595
Associated With corin Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR001190 SRCR domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR020067 Frizzled domain
Domain IPR041762 Corin, cysteine-rich domain 1
Domain IPR041763 Corin, cysteine-rich domain 2
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036772 SRCR-like domain superfamily
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length Corin, cysteine-rich domain 1 Corin, cysteine-rich domain 2 Frizzled cysteine-rich domain superfamily Frizzled domain LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, serine active site SRCR domain SRCR-like domain superfamily
UniProtKB:A0A0R4IA13 833
UniProtKB:A0A0R4IGX1 751
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations