ZFIN ID: ZDB-GENE-060217-1
Gene Name: leucine-rich, glioma inactivated 1b
Gene Symbol: lgi1b
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
  brain, cerebellum, diencephalon, dorsal thalamus (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa131 Point Mutation ENU
sa22016 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-lgi1b (1)
    PHENOTYPE
    Data: 3 figures from Teng et al., 2011
    Observed in: brain, brain morphogenesis, eye, forebrain (all 6) expand
    DISEASE ASSOCIATED WITH lgi1b HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Epilepsy, familial temporal lobe, 1 600512
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process myelination (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR005492 (1)
  • InterPro:IPR009039 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS50912 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF03736 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lgi1b-001 (1) 2019
    lgi1b-002 (1) 541
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lgi1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    lgi1bContained in: [BAC] CH211-197G18 (1) (order this)
    lgi1bEncodes: [cDNA] MGC:195239 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128769 (1) 2019bp
    Genomic GenBank:CU463858 (1) 68987bp
    Select Tool
    Polypeptide UniProtKB:B3DJS9 (1) 543aa
    Sequence Clusters UniGene:94490 (1)
    Sequence Information (all 15)
    OTHER lgi1b GENE PAGES 
  • Gene:654829 (1)
  • VEGA:OTTDARG00000035679 (1)
  • Ensembl(GRCz10):ENSDARG00000058421 (1)
  • ORTHOLOGY for lgi1b (Chr: 12) 
    Species Symbol Chromosome Accession # Evidence
    Human LGI1 10
  • Gene:9211
  • OMIM:604619
  • HGNC:6572
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (14)