ZFIN ID: ZDB-GENE-060217-1
Gene Name: leucine-rich, glioma inactivated 1b
Gene Symbol: lgi1b
Location: Chr: 12   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
  brain, eye, heart, skeletal muscle (all 5) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa131, sa22016
Knockdown reagents: MO1-lgi1b (1)
PHENOTYPE
Data: 3 figures from Teng et al., 2011
Observed in: brain, brain morphogenesis, eye, forebrain (all 6) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Epilepsy, familial temporal lobe, 1 600512
GENE ONTOLOGY
Ontology GO Term
Biological Process myelination (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR005492 (1)
  • InterPro:IPR009039 (1)
  • PROSITE:PS50912 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF03736 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lgi1b-001 (1) 2019
    lgi1b-002 (1) 541
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lgi1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lgi1b Contained in: [BAC] CH211-197G18 (1) (order this)
    lgi1b Encodes: [cDNA] MGC:195239 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128769 (1) 2019 bp
    Genomic GenBank:CU463858 (1) 68987 bp
    Select Tool
    Polypeptide UniProtKB:B3DJS9 (1) 543 aa
    Sequence Clusters UniGene:94490 (1)
    Sequence Information (all 15)
    OTHER lgi1b GENE PAGES
  • Gene:654829 (1)
  • VEGA:OTTDARG00000035679 (1)
  • Ensembl(Zv9):ENSDARG00000058421 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish lgi1b 12  
    Human LGI1 10 (10q24)
  • OMIM:604619
  • Gene:9211
  • Orthology Details
    CITATIONS (14)