ZFIN ID: ZDB-GENE-060217-1
Gene Name: leucine-rich, glioma inactivated 1b
Gene Symbol: lgi1b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Involved in brain morphogenesis and myelination. Is expressed in brain; eye; head mesenchyme; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in childhood absence epilepsy and familial temporal lobe epilepsy 1. Orthologous to several human genes including LGI1 (leucine rich glioma inactivated 1).
Genome Resources: Alliance (1),  Gene:654829 (1),  Ensembl(GRCz11):ENSDARG00000058421 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa131 Point Mutation Unknown Unknown ENU
sa19023 Point Mutation Unknown Premature Stop ENU
sa22016 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41952 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45447 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lgi1b N/A 1
    DISEASE ASSOCIATED WITH lgi1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    familial temporal lobe epilepsy 1 Alliance Epilepsy, familial temporal lobe, 1 600512
    DISEASE ASSOCIATED WITH lgi1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myelination (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lgi1b-201 (1)    Ensembl 2019
    lgi1b-202 (1)    Ensembl 541
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lgi1b No data available
    MARKER RELATIONSHIPS
    lgi1b Contained in: [BAC] CH211-197G18 (1)
    lgi1b Encodes: [cDNA] MGC:195239 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128769 (1) 2019 nt
    Genomic GenBank:CU463858 (1) 68987 nt
    Select Tool
    Polypeptide UniProtKB:B3DJS9 (1) 543 aa
    Sequence Information (all 15)
    ORTHOLOGY for lgi1b ( Chr: 12 )
    CITATIONS (22)