ZFIN ID: ZDB-GENE-060217-1
Gene Name: leucine-rich, glioma inactivated 1b
Gene Symbol: lgi1b

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Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
  brain, cerebellum, diencephalon, dorsal thalamus (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa131 Point Mutation Unknown Unknown ENU
sa19023 Point Mutation Unknown Premature Stop ENU
sa22016 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41952 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-lgi1b (1)
    PHENOTYPE
    Data: 3 figures from Teng et al., 2011
    Observed in: brain, brain morphogenesis, eye, forebrain (all 6) expand
    DISEASE ASSOCIATED WITH lgi1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Epilepsy, familial temporal lobe, 1 600512
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myelination (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR005492 (1)
  • InterPro:IPR009039 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS50912 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF03736 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lgi1b-001 (1) 2019
    lgi1b-002 (1) 541
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lgi1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lgi1bContained in: [BAC] CH211-197G18 (1) (order this)
    lgi1bEncodes: [cDNA] MGC:195239 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128769 (1) 2019bp
    Genomic GenBank:CU463858 (1) 68987bp
    Select Tool
    Polypeptide UniProtKB:B3DJS9 (1) 543aa
    Sequence Clusters UniGene:94490 (1)
    Sequence Information (all 15)
    OTHER lgi1b GENE PAGES
  • Gene:654829 (1)
  • VEGA:OTTDARG00000035679 (1)
  • Ensembl(GRCz10):ENSDARG00000058421 (1)
  • ORTHOLOGY for lgi1b (Chr: 12)
    Species Symbol Chromosome Accession # Evidence
    Human LGI1 10
  • Gene:9211
  • OMIM:604619
  • HGNC:6572
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (14)