Gene

asip1

ID
ZDB-GENE-060215-1
Name
agouti signaling protein 1
Symbol
asip1 Nomenclature History
Previous Names
  • asip
  • zgc:194136 (1)
  • zgc:194144 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have signaling receptor binding activity. Involved in pigmentation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including fat cell; integument; liver; opercle; and pleuroperitoneal region. Orthologous to human ASIP (agouti signaling protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Cal et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With asip1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Skin/hair/eye pigmentation 9, brown/nonbrown eyes] 611742
[Skin/hair/eye pigmentation 9, dark/light hair] 611742
Associated With asip1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR027300 Agouti domain
Family IPR007733 Agouti
Homologous_superfamily IPR036836 Agouti domain superfamily
Domain Details Per Protein
Protein Length Agouti Agouti domain Agouti domain superfamily
UniProtKB:B3DGI7 125
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations