Gene
asip1
- ID
- ZDB-GENE-060215-1
- Name
- agouti signaling protein 1
- Symbol
- asip1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable melanocortin receptor binding activity and neuropeptide hormone activity. Acts upstream of or within pigmentation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including fat cell; integument; liver; opercle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in pigmentation disease and type 2 diabetes mellitus. Orthologous to human ASIP (agouti signaling protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Cal et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Agouti | Agouti domain | Agouti domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:B3DGI7 | InterPro | 125 | |||
| UniProtKB:A0A8M3ATM6 | InterPro | 102 | |||
| UniProtKB:A0AB32TTC4 | InterPro | 138 |
Interactions and Pathways
No data available
Plasmids
No data available