Gene

ifng1r

ID
ZDB-GENE-060210-1
Name
interferon gamma related
Symbol
ifng1r Nomenclature History
Previous Names
  • ifng1-1
  • Ifng1 (1)
  • Ifngamma1 (1)
  • si:ch211-266a5.1 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have interferon-gamma receptor binding activity. Involved in defense response to Gram-negative bacterium and immune response. Predicted to localize to extracellular region. Is expressed in digestive system; gill; reproductive system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; factor VIII deficiency; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).
Genome Resources
Note
None
Expression
All Expression Data
12 figures from 10 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
text only from Sieger et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ifng1r Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aplastic anemia Alliance {Aplastic anemia} 609135
immunodeficiency 69 Alliance ?Immunodeficiency 69, mycobacteriosis 618963
tuberous sclerosis 2 Alliance {TSC2 angiomyolipomas, renal, modifier of} 613254
{AIDS, rapid progression to} 609423
{Hepatitis C virus, response to therapy of} 609532
{Tuberculosis, protection against} 607948
Associated With ifng1r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002069 Interferon gamma
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Four-helical cytokine-like, core Interferon gamma
UniProtKB:Q5TLE6 170
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations