Gene

ifng1r

ID
ZDB-GENE-060210-1
Name
interferon gamma related
Symbol
ifng1r Nomenclature History
Previous Names
  • ifng1-1
  • Ifng1 (1)
  • Ifngamma1 (1)
  • si:ch211-266a5.1 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have interferon-gamma receptor binding activity. Involved in defense response to Gram-negative bacterium and immune response. Predicted to localize to extracellular region. Is expressed in digestive system; gill; reproductive system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; factor VIII deficiency; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sieger et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ifng1r Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aplastic anemia Alliance {Aplastic anemia} 609135
immunodeficiency 69 Alliance ?Immunodeficiency 69, mycobacteriosis 618963
tuberous sclerosis 2 Alliance {TSC2 angiomyolipomas, renal, modifier of} 613254
{AIDS, rapid progression to} 609423
{Hepatitis C virus, response to therapy of} 609532
{Tuberculosis, protection against} 607948
Associated With ifng1r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002069 Interferon gamma
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Four-helical cytokine-like, core Interferon gamma
UniProtKB:Q5TLE6 170
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ifng1r-201 (1) Ensembl 513 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations