ZFIN ID: ZDB-GENE-060208-1
Gene Name: glutamate receptor, metabotropic 6a
Gene Symbol: grm6a    Nomenclature History

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Previous Names: grm6, mglur6a (1), si:dkey-52h10.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain and retinal neural layer. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1B. Orthologous to human GRM6 (glutamate metabotropic receptor 6).
Genome Resources: Alliance (1),  Gene:568484 (1),  Ensembl(GRCz11):ENSDARG00000017742 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026701Tg Transgenic Insertion Unknown Unknown DNA
sa21200 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grm6a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital stationary night blindness 1B Alliance Night blindness, congenital stationary (complete), 1B, autosomal recessive 257270
    DISEASE ASSOCIATED WITH grm6a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function group III metabotropic glutamate receptor activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grm6a-201 (1)    Ensembl 2724
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grm6a No data available
    MARKER RELATIONSHIPS
    grm6a Contained in: [BAC] DKEY-52H10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001123292 (1) 2724 nt
    Genomic GenBank:CR457452 (1) 232104 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IRN2 (1) 908 aa
    Sequence Information (all 11)
    ORTHOLOGY for grm6a ( Chr: 8 )
    CITATIONS (22)